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– Nelson Mandela

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Week 8 Lab Activity

Week 8 Lab Activity

Q Questions from Readings 1. You may have seen or heard the term “Hygiene Hypothesis” in the media or in past readings. Why might this term be misleading? 2. Why is it suggested that infection by certain parasitic worms may have a positive impact on patients suffering from immune-related diseases? 3. What is meant by the term, “evolutionary mismatch?”Data Analysis For this lab, you will need to submit your graphs for the IL-10 and T-reg data. You can submit these separately as Excel files in Canvas or you can copy and paste the graphs themselves here: Experimental Questions 1. What were the independent and dependent variables in the experiment? 2. What were the hypotheses and experimental predictions? In your predictions, remember to describe what you expected to happen (based on your hypothesis) to IL-10 levels, T-reg cell numbers, and numbers of exacerbations for your treated vs. untreated patient groups.

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1.Response: According to the hygiene hypothesis, exposure to germs and some diseases throughout childhood aids immune system development. This is misleading because there are certain diseases that do not justify the hypothesis. For example, asthma is not necessarily influenced by exposure to genus rather it is influenced much before during the child is in the womb of the mother. 2.Response: it is suggested infection by certain parasitic worms have a positive impact on patients suffering from the immune related disease because the exposure to the worm helps in eliciting an immune response and helps the host in preventing from future exposures.